Occupational medicine (Oxford, England) · 2006
University of Toronto case-control study of multiple chemical sensitivity-3: intra-erythrocytic mineral levels.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Baines Cornelia J, McKeown-Eyssen Gail E, Riley Nicole, Marshall Lynn, Jazmaji Vartouhi
Аннотация
BACKGROUND: Multiple chemical sensitivity (MCS) has an estimated American prevalence of 15%, and no consistently abnormal laboratory tests are available to assist in its diagnosis. Some physicians treating MCS patients have observed changes in intra-erythrocytic minerals (IEMs). As co-factors, minerals could influence detoxication of xenobiotics.
AIM: To test whether IEM differed comparing MCS cases with controls.
METHODS: A total of 408 women meeting validated inclusion and exclusion criteria for MCS participated in this case-control study.
RESULTS: No statistically significant differences were observed. However, for copper, chromium, magnesium, molybdenum, sulphur and zinc, mean detectable levels were all lower in cases. No dose-response relationships were found.
CONCLUSION: IEM measurements do not appear to provide useful diagnostic markers for MCS.
AIM: To test whether IEM differed comparing MCS cases with controls.
METHODS: A total of 408 women meeting validated inclusion and exclusion criteria for MCS participated in this case-control study.
RESULTS: No statistically significant differences were observed. However, for copper, chromium, magnesium, molybdenum, sulphur and zinc, mean detectable levels were all lower in cases. No dose-response relationships were found.
CONCLUSION: IEM measurements do not appear to provide useful diagnostic markers for MCS.