Медицинская библиотека · Occupational medicine (Oxford, England) · 2006

University of Toronto case-control study of multiple chemical sensitivity-3: intra-erythrocytic mineral levels.

Baines Cornelia J, McKeown-Eyssen Gail E, Riley Nicole, Marshall Lynn, Jazmaji Vartouhi

Сравнительное исследованиеСтатьяПеревод в очереди

Аннотация

BACKGROUND

Multiple chemical sensitivity (MCS) has an estimated American prevalence of 15%, and no consistently abnormal laboratory tests are available to assist in its diagnosis. Some physicians treating MCS patients have observed changes in intra-erythrocytic minerals (IEMs). As co-factors, minerals could influence detoxication of xenobiotics.

AIM: To test whether IEM differed comparing MCS cases with controls.

METHODS

A total of 408 women meeting validated inclusion and exclusion criteria for MCS participated in this case-control study.

RESULTS

No statistically significant differences were observed. However, for copper, chromium, magnesium, molybdenum, sulphur and zinc, mean detectable levels were all lower in cases. No dose-response relationships were found.

CONCLUSION

IEM measurements do not appear to provide useful diagnostic markers for MCS.

Для цитирования: Baines Cornelia J, McKeown-Eyssen Gail E, Riley Nicole, Marshall Lynn, Jazmaji Vartouhi. University of Toronto case-control study of multiple chemical sensitivity-3: intra-erythrocytic mineral levels.. Occupational medicine (Oxford, England). 2006. DOI: 10.1093/occmed/kql104.

Предметные рубрики MeSH

Adult Case-Control Studies Erythrocytes Female Humans Logistic Models Middle Aged Minerals Multiple Chemical Sensitivity Ontario

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