Metal-free synthesis of α-keto-N-acyl sulfoximines from sulfoximines and α-bromomethyl aryl ketones under photoredox catalysis.

In this study, we describe a metal-free and mild strategy to prepare α-keto-N-acyl sulfoximines by reacting sulfoximines with α-bromomethyl aryl ketones under green LED light with eosin Y as a photocatalyst. The protocol requires no external oxidants and forms new C-O and C-N bonds, offering a sustainable, efficient approach for constructing valuable sulfoximine-based organic frameworks.