Journal of opioid management · 2016
Transient low testosterone levels after oral hydrocodone may contribute to misdiagnosis of hypogonadism.
СтатьяНазвание и аннотация: Перевод в очереди
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Daniell Harry W
Аннотация
CONTEXT: Multiple morning testosterone levels are needed to establish the presence of male hypogonadism and to justify its replacement therapy. Any influence on these levels by short-term opioid ingestion has not, however, been reported.
CASE DESCRIPTION: Serial testosterone levels are reported at 2-hour intervals once weekly for 22 weeks in a man after his ingestion of 0, 5, or 10 mg of hydrocodone.
CONCLUSIONS: Five milligrams of hydrocodone did not significantly alter postingestion testosterone levels, but 10 mg ingestion lowered them at 2, 4, and 6 hours postingestion.
CASE DESCRIPTION: Serial testosterone levels are reported at 2-hour intervals once weekly for 22 weeks in a man after his ingestion of 0, 5, or 10 mg of hydrocodone.
CONCLUSIONS: Five milligrams of hydrocodone did not significantly alter postingestion testosterone levels, but 10 mg ingestion lowered them at 2, 4, and 6 hours postingestion.