EA-rosette test in cervical cell suspensions.

Use of the EA-rosette test to detect the presence or absence of cells with an Fc receptor is proposed as a method of screening for cancerous cells and cells of carcinoma in situ in suspensions of cervical cell populations, The EA-rosette test was performed on cervical cell suspensions from 2,437 patients. In 54% the rosette test was negative; i.e., no EA rosettes were observed in the cervical cell suspensions. The EA-rosette test was positive in 46% of the cases, within which most cells with severe dysplastic and carcinomatous features were found. The predictive value for the negative EA-rosette test was 99.8%.