Journal of conservative dentistry and endodontics · 2026
Antibacterial efficacy of calcium hydroxide, polyantibiotic paste, and Laccifer lacca combinations: An in vitro study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sreelekshmi S G, Vineet R V, Pillai Rajesh, Afsal A, Arun Charutha, Syanth Aarathy
Аннотация
BACKGROUND: Persistent Enterococcus faecalis infections compromise root canal therapy, with conventional medicaments like calcium hydroxide showing limited efficacy due to bacterial resistance. Novel combinations may improve disinfection outcomes.
OBJECTIVE: To compare the antibacterial efficacy of calcium hydroxide with Laccifer lacca, calcium hydroxide alone, and a polyantibiotic paste (Neosporin-H) against E. faecalis.
METHODS: Twenty-eight extracted mandibular premolars were prepared and inoculated with E. faecalis for 21 days. Specimens were divided into four groups: calcium hydroxide, calcium hydroxide + Laccifer lacca (6:4 ratio), Neosporin-H, and untreated controls. After 7 days of medicament placement, dentin scrapings were cultured to assess colony-forming units (CFUs). Statistical analysis was performed using one-way ANOVA.
RESULTS: CFUs were highest in controls (318.00), reduced with calcium hydroxide (204.57), and further lowered by Neosporin-H (143.00). The calcium hydroxide + Laccifer lacca group showed the greatest reduction (7.71 CFUs; F = 49.64, P = 0.0001).
CONCLUSION: Laccifer lacca significantly enhances calcium hydroxide's antibacterial activity, offering a promising alternative intracanal medicament for resistant E. faecalis infections.
OBJECTIVE: To compare the antibacterial efficacy of calcium hydroxide with Laccifer lacca, calcium hydroxide alone, and a polyantibiotic paste (Neosporin-H) against E. faecalis.
METHODS: Twenty-eight extracted mandibular premolars were prepared and inoculated with E. faecalis for 21 days. Specimens were divided into four groups: calcium hydroxide, calcium hydroxide + Laccifer lacca (6:4 ratio), Neosporin-H, and untreated controls. After 7 days of medicament placement, dentin scrapings were cultured to assess colony-forming units (CFUs). Statistical analysis was performed using one-way ANOVA.
RESULTS: CFUs were highest in controls (318.00), reduced with calcium hydroxide (204.57), and further lowered by Neosporin-H (143.00). The calcium hydroxide + Laccifer lacca group showed the greatest reduction (7.71 CFUs; F = 49.64, P = 0.0001).
CONCLUSION: Laccifer lacca significantly enhances calcium hydroxide's antibacterial activity, offering a promising alternative intracanal medicament for resistant E. faecalis infections.