Clinical neuropharmacology · 2006
Reversible tremor, myoclonus, and fasciculations associated with topiramate use for migraine.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Alonso-Navarro Hortensia, Jiménez-Jiménez Félix Javier
Аннотация
OBJECTIVE: To report a patient with tremor, multifocal myoclonus, and fasciculations, possibly induced by the antiepileptic drug topiramate.
CASE REPORT: A 46-year-old woman with frequent episodes of migraine without aura that were not controlled with other prophylactic drug, developed a reversible clinical picture of postural tremor, multifocal myoclonus, weight loss, amyotrophia, and fasciculations after exposure to topiramate. These symptoms disappeared after topiramate withdrawal.
CONCLUSIONS: Tremor, myoclonus, and fasciculations should be considered as a possible adverse effect of topiramate.
CASE REPORT: A 46-year-old woman with frequent episodes of migraine without aura that were not controlled with other prophylactic drug, developed a reversible clinical picture of postural tremor, multifocal myoclonus, weight loss, amyotrophia, and fasciculations after exposure to topiramate. These symptoms disappeared after topiramate withdrawal.
CONCLUSIONS: Tremor, myoclonus, and fasciculations should be considered as a possible adverse effect of topiramate.