Enhancing chronic kidney disease care through risk prediction: A review of the kidney failure risk equation.

Chronic kidney disease (CKD) is a growing global health problem, with projections indicating a significant increase in its prevalence. The kidney failure risk equation (KFRE) has emerged as a valuable predictive tool to assess the risk of kidney failure in patients with CKD stages 3-5. This narrative review presents a comprehensive analysis of the KFRE's development, validation, and clinical applications, and highlights its role in predicting disease progression, guiding nephrology referrals, and planning vascular access creation.