The relationship between calcium content and aluminum and silicon content in uraemic rats.

The relationship between calcium (Ca) content and aluminum (Al) and silicon (Si) content in uraemic rats was examined. Significant correlations with serum [Ca] x [Pi] products and serum Al levels and serum Si values were found (r = 0.73, p less than 0.01). There were significant (r = -0.26, p less than 0.05; r = -0.46, p less than 0.05) relationships between corpuscular [Ca] x [Pi] products and corpuscular Al levels and corpuscular Si values. We found that renal tissue [Ca] x [Pi] products tend to increase with the increase of renal tissue Al content and renal tissue Si content. Serum and corpuscular Al content and Si content can be used as one of the indicators of renal osteodystrophy.