[Blood tests in the first trimester of pregnancy: what to screen?].

Screening in early pregnancy of some potential diseases has led to the improvement of the health of mothers and newborns. Recommended tests vary from one country to another. We presented the screening recommendations of screening proposed in the " Guide de Consultation Prénatale" (published in 2009) by the GGOLFB and ONE and put it in perspective with the recommendations of the KCE, the NICE of England, the HAS of France and the RANZCOG of Australia and New Zealand. It appears that at the first antenatal visit for pregnant women without particular risk factor, a full blood examination, serological screening for rubella, cytomegalovirus, toxoplasmosis, HIV, HBV the HCV and syphilis as well as an evaluation of the thyroid function are recommended screening tests. Finally, depending on the chosen strategy for gestational diabetes screening, a fasting glycemia might be proposed. As these recommendations are mainly based on studies of low level of evidence, future studies could change the currently proposed screening strategies.