[Syphilis: clinical, biological and therapeutical aspects].

Syphilis is a STI. The present epidemic is related to the relapse into unsafe sexual behaviour. HIV has not modified clinical aspects and the great simulator implies to perform TPHA and VDRL in various circumstances. Treatment is simple and consensual in early syphilis. Treatment of late syphilis is dependent upon indications of CSF control, to be discussed by specialists, particularly in HIV+ patients.