Heparin successfully improved an early onset intrauterine growth restriction accompanied by severe oligohydramnios.

Oligohydramnios is an ominous pregnant complication with high perinatal morbidity and mortality of 80%-90%, if it was observed in second trimester. However, there is no promising modality to cure it at that period. In this case, heparin therapy was successful in an early onset extreme oligohydramnios.