Jaundice, an Early Clinical Manifestation of Secondary Syphilis.

Hepatitis is an uncommon manifestation of early acquired syphilis. A case of secondary syphilis presenting with jaundice and papular eruption is reported. The icterus was slight and responded romptly to penicillin therapy, transaminase levels were moderately increased. Alkaline phosphatase was elevated. Jaundice was due to an inc of both conjugated and unconjugated bilirubin; serological reactions for syphilis were positive.