Revista da Sociedade Brasileira de Medicina Tropical · 2022
Asymptomatic Neurosyphilis in HIV infected patients at a Brazilian HIV and AIDS specialized service: a cross sectional study.
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Hirai Cláudio Queniti, Moreira Deborah de Castro, Granzotto Danielle Cristina Tita, Souza Eniuce Menezes de, Teixeira Jorge Juarez Vieira, Bertolini Dennis Armando
Аннотация
BACKGROUND: Many human immunodeficiency virus (HIV) and syphilis co-infected patients are not diagnosed, which may evolve into asymptomatic neurosyphilis (ANS). We studied the occurrence of ANS an HIV-infected population.
METHODS: This was a cross-sectional study of cerebrospinal fluid (CSF) samples collected from patients co-infected with HIV and Treponema pallidum. Social-demographic and clinical-laboratory characteristics were studied.
RESULTS: Of the 348 patients infected with HIV, 33 (9.5%) had reagent treponemic and non-treponemic tests. CSF was collected from 19 asymptomatic patients. Of these, 8 (42.1%) presented with laboratory alterations suggestive of ANS.
CONCLUSION: Social-demographic and clinical-laboratory variables should be considered for the indication of CSF collection.
METHODS: This was a cross-sectional study of cerebrospinal fluid (CSF) samples collected from patients co-infected with HIV and Treponema pallidum. Social-demographic and clinical-laboratory characteristics were studied.
RESULTS: Of the 348 patients infected with HIV, 33 (9.5%) had reagent treponemic and non-treponemic tests. CSF was collected from 19 asymptomatic patients. Of these, 8 (42.1%) presented with laboratory alterations suggestive of ANS.
CONCLUSION: Social-demographic and clinical-laboratory variables should be considered for the indication of CSF collection.