Медицинская библиотека · Allergy · 2000

A 17-kDa allergen detected in pine nuts.

García-Menaya J M, Gonzalo-Garijo M A, Moneo I, Fernández B, García-González F, Moreno F

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Аннотация

BACKGROUND

Few cases of allergy to pine nuts have been described. We report a case of anaphylactic reaction to pine nuts. The patient needed to be treated in the emergency room due to a systemic reaction immediately after eating pine nuts.

METHODS

The patient was studied by prick tests and prick by prick tests. Specific IgE was measured by CAP and by SDS-PAGE/immunoblotting by a diffusion method.

RESULTS

The patient showed positive prick by prick tests to pine nuts (12 mm of maximum wheal diameter). Specific IgE was positive (0.79 kU/l). The patient's serum recognized several proteins by immunoblot. However, a 17-kDa allergen band was detected with high intensity. This protein was found to be sensitive to reducing agents, losing its IgE-binding properties after reduction.

CONCLUSIONS

The patient presented an IgE-mediated reaction and detected a 17-kDa protein from pine nuts not previously described.

Для цитирования: García-Menaya J M, Gonzalo-Garijo M A, Moneo I, Fernández B, García-González F, Moreno F. A 17-kDa allergen detected in pine nuts.. Allergy. 2000. DOI: 10.1034/j.1398-9995.2000.00291.x.

Предметные рубрики MeSH

Adult Allergens Anaphylaxis Electrophoresis, Polyacrylamide Gel Food Hypersensitivity Humans Immunoblotting Immunoglobulin E Intradermal Tests Male Molecular Weight Nuts Plant Proteins

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