Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2014
[In vitro effect of psychotropic drugs on the activity of leukocyte elastase].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Androsova L V, Shmakova A A
Аннотация
OBJECTIVE: To investigate the effect of the neuroleptic aminazine (chlorpromazine) and the antidepressant melipramine on the activity of leukocyte elastase (LE).
METHODS: The LE activity was measured on a spectrophotometer. Different doses of aminazine and melipramine in terms of therapeutic doses were added to the pooled blood serum sampled from 7 healthy people.
RESULTS: Aminazine and melipramine inhibited the LE activity.
CONCLUSIONS: The dose-dependent inhibiting effect of aminazine and melipramine was shown.
METHODS: The LE activity was measured on a spectrophotometer. Different doses of aminazine and melipramine in terms of therapeutic doses were added to the pooled blood serum sampled from 7 healthy people.
RESULTS: Aminazine and melipramine inhibited the LE activity.
CONCLUSIONS: The dose-dependent inhibiting effect of aminazine and melipramine was shown.