[Neurosyphilis and HIV co-infection with the initial symptom of sudden deafness and optic atrophy: a case report].

A 46-year-old male presented with left ear hearing loss,vertigo,tinnitus and left eye blurred vision. Pure tone audiometry showed left ear had been total deafness. Treponema pallidum particle agglutination (TPPA) assay was reactive. The serum rapid plasma regain (RPR) was 1∶16. Human immunodeficiency virus(HIV) 1/2 antibody immunoassay was positive，and the CD4 cell count was low at 100 cells/μl. Cerebrospinal fluid (CSF) TPPA was positive,with a white blood cell count of 53×10 ⁶ /L and protein level of 1.08 g/L.The diagnosis was:①left ear sudden deafness(total deafness type);②neurosyphilis;③acquired immune deficiency syndrome(AIDS).