Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases · 2007
[Dose-effect relationship between premature chromosome and irradiation dose].
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Jiang Bo, Liu Qiang, Jiang En-Hai, Xing Zhi-Wei, Zhao Xin-Ran
Аннотация
OBJECTIVE: To explore the dose-effect relationship between premature chromosome condensation induced by Calyculin A and irradiation dose.
METHODS: The human peripheral blood was irradiated by (137)Cs gamma radial. The irradiation dose included 0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 Gy. The premature chromosome condensation induced by Calyculin A was observed, and dyed by centromeric banding.
RESULTS: There was the quadratic relation between the total aberration, fragment, dicentric+centric ring (dic+r) ration and irradiation dose.
CONCLUSION: Premature chromosome condensation induced by Calyculin A can be used as a biodosimetry.
METHODS: The human peripheral blood was irradiated by (137)Cs gamma radial. The irradiation dose included 0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 Gy. The premature chromosome condensation induced by Calyculin A was observed, and dyed by centromeric banding.
RESULTS: There was the quadratic relation between the total aberration, fragment, dicentric+centric ring (dic+r) ration and irradiation dose.
CONCLUSION: Premature chromosome condensation induced by Calyculin A can be used as a biodosimetry.