Медицинская библиотека · Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases · 2007

[Dose-effect relationship between premature chromosome and irradiation dose].

Jiang Bo, Liu Qiang, Jiang En-Hai, Xing Zhi-Wei, Zhao Xin-Ran

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

To explore the dose-effect relationship between premature chromosome condensation induced by Calyculin A and irradiation dose.

METHODS

The human peripheral blood was irradiated by (137)Cs gamma radial. The irradiation dose included 0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 Gy. The premature chromosome condensation induced by Calyculin A was observed, and dyed by centromeric banding.

RESULTS

There was the quadratic relation between the total aberration, fragment, dicentric+centric ring (dic+r) ration and irradiation dose.

CONCLUSION

Premature chromosome condensation induced by Calyculin A can be used as a biodosimetry.

Для цитирования: Jiang Bo, Liu Qiang, Jiang En-Hai, Xing Zhi-Wei, Zhao Xin-Ran. [Dose-effect relationship between premature chromosome and irradiation dose].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2007.

Предметные рубрики MeSH

Cell Line Chromosome Aberrations Chromosome Banding Chromosomes Dose-Response Relationship, Radiation Female Gamma Rays Humans Lymphocytes Male Marine Toxins Oxazoles Young Adult

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