Akusherstvo i ginekologiia · 2005
[Medical abortion using methotrexate and misoprostol. Efficacy and tolerability].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Iamakov K, Pekhlivanov B, Amaliev I
Аннотация
UNLABELLED: Medical abortion means interruption of early pregnancy (usually before 9-th gestational week) as a result of administration of abortifacient drugs without surgical intervention.
OBJECTIVE: To investigate the efficacy and tolerability of methotrexate plus misoprostol regimen as a method for early medical abortion < 49 days L.M.P.
MATERIAL AND METHOD: 50 mg methotrexate was administered orally to 20 women < 49 days L.M.P. followed by 800 mcg misoprostol vaginal and oral administration 3-7 days after the methotrexate.
RESULTS: 19 Successful medical abortions (95%). One woman chose vacuum aspiration for termination of the abortion on day 3 of the induced bleeding. No serious side effects were observed after administration of the drugs.
CONCLUSION: Medical abortion with methotrexate and misoprostol is safe and effective and can be offered to practicing gynecologists.
OBJECTIVE: To investigate the efficacy and tolerability of methotrexate plus misoprostol regimen as a method for early medical abortion < 49 days L.M.P.
MATERIAL AND METHOD: 50 mg methotrexate was administered orally to 20 women < 49 days L.M.P. followed by 800 mcg misoprostol vaginal and oral administration 3-7 days after the methotrexate.
RESULTS: 19 Successful medical abortions (95%). One woman chose vacuum aspiration for termination of the abortion on day 3 of the induced bleeding. No serious side effects were observed after administration of the drugs.
CONCLUSION: Medical abortion with methotrexate and misoprostol is safe and effective and can be offered to practicing gynecologists.