[Severe Intracranial Hemorrhage Secondary to Hemorrhagic Diathesis Following the Use of a Tablet Containing Schisandra Chinensis: A Case Report].

The use of alternative medicine treatments, such as Schisandra chinensis, has a long-standing history. While numerous active compounds are available on the market, with various benefits attributed to their use, reports of adverse events remain limited. However, significant interactions have been documented between these compounds and the CYP3A enzymatic system, which plays a key role in the metabolism of xenobiotics and endogenous substances. Inactivation of this system has the potential to disrupt coagulation processes, posing serious health risks. Clinical Case: We report the case of a patient who developed spontaneous subdural and subarachnoid hemorrhage and de novo immune thrombocytopenia following the initiation of a multi-component tablet containing Schisandra chinensis.

Conclusions

The indiscriminate use of alternative medicine therapies may result in severe, acute, and disabling adverse effects, even in the absence of prior reports of such reactions. Increased awareness and further research are essential to better understand the potential risks associated with these treatments.