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DOI 10.1016/j.ajog.2009.10.859

Медицинская библиотека · American journal of obstetrics and gynecology · 2009

The effect of maternal body mass index on neonatal outcome in women receiving a single course of antenatal corticosteroids.

Hashima Jason N, Lai Yinglei, Wapner Ronald J, Sorokin Yoram, Dudley Donald J, Peaceman Alan, Spong Catherine Y, Iams Jay D, Leveno Kenneth J, Harper Margaret, Caritis Steve N, Varner Michael, Miodovnik Menachem, Mercer Brian M, Thorp John M, O'Sullivan Mary J, Ramin Susan M, Carpenter Marshall, Rouse Dwight J, Sibai Baha, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network

СтатьяРандомизированное исследованиеПоддержка NIH: внешняя программаПеревод в очереди

Аннотация

OBJECTIVE

The aim of this study was to determine the effect of maternal body mass index on the incidence of neonatal prematurity morbidities in those who receive corticosteroids.

STUDY

DESIGN

This was a secondary analysis of a trial of corticosteroids in women at risk for preterm birth. Women receiving a single course of corticosteroids were classified by their prepregnancy body mass index (<25 and > or = 25) and compared on a composite outcome comprised of several neonatal morbidities and on each individual outcome.

RESULTS

Of 183 eligible women, 96 (52.5%) had a body mass index of <25 and 87 (47.5%) had a body mass index of > or = 25. The composite outcome occurred more frequently in the body mass index of > or = 2 5 group (28.7%), compared with those with a body mass index of <25 (18.8%), although this was not statistically significant (odds ratio, 1.75; 95% confidence interval, 0.83-3.72). Body mass index was not associated with outcomes after adjusting for confounding.

CONCLUSION

Maternal body mass index did not affect neonatal prematurity morbidities in those receiving corticosteroids.

Для цитирования: Hashima Jason N, Lai Yinglei, Wapner Ronald J, Sorokin Yoram, Dudley Donald J, Peaceman Alan, Spong Catherine Y, Iams Jay D, Leveno Kenneth J, Harper Margaret, Caritis Steve N, Varner Michael, Miodovnik Menachem, Mercer Brian M, Thorp John M, O'Sullivan Mary J, Ramin Susan M, Carpenter Marshall, Rouse Dwight J, Sibai Baha, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. The effect of maternal body mass index on neonatal outcome in women receiving a single course of antenatal corticosteroids.. American journal of obstetrics and gynecology. 2009. DOI: 10.1016/j.ajog.2009.10.859.

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