68Ga-DOTANOC PET-CT demonstrating in vivo somatostatin receptor expression in idiopathic gynecomastia.

Gynecomastia is abnormal enlargement of the male breasts due to the excess growth of glandular component. A 65-year-old man with medullary carcinoma of thyroid underwent (68)Ga-DOTANOC PET-CT for somatostatin receptor (SSTR) scintigraphy. Extensive nodal, bone, and bone marrow disease was seen. Interestingly, increased (68)Ga-DOTANOC uptake was also noted in bilateral enlarged mammary glands (gynecomastia). Although SSTR types 1 and 3 have been identified in the normal female breast, no report exists regarding SSTR expression in gynecomastia.