Rare Metastatic Involvement of the Sigmoid Mesocolon by Low-Grade Endometrial Stromal Sarcoma.

INTRODUCTION

Endometrial stromal sarcoma (ESS) is an uncommon uterine malignancy with an indolent course and potential for late recurrence or metastasis. Extrauterine ESS is exceedingly rare, especially in the absence of a primary uterine lesion.

CASE PRESENTATION: We present a case of a 50-year-old woman with low-grade ESS metastasizing to the sigmoid mesocolon. The patient underwent surgical resection followed by radical hysterectomy, bilateral salpingo-oophorectomy, and hormonal therapy with letrozole. After 5 years of follow-up, she remains disease-free.

DISCUSSION: This case underscores the importance of considering ESS in the differential diagnosis of mesocolon masses and highlights the role of combined surgical and hormonal therapy in achieving long-term remission.