Cardiac Arrest From Undiagnosed Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report.

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inherited heart disease in which exercise or acute emotional stress can cause potentially fatal tachyarrhythmias. We present the case of a 16-year-old female patient with a history of unexplained palpitations and syncope who suddenly collapsed in her high school cafeteria following an impassioned debate. In cardiac arrest consisting of coarse ventricular fibrillation, she was resuscitated on-scene by the school nurse via automated external defibrillation. Months later, after substantial investigation, a diagnosis of CPVT was reached. The patient made a full neurological recovery, and one year post-arrest, she was event-free on β-blocker therapy. This case demonstrates the importance of clinician awareness of CPVT, an unusual but treatable cause of cardiac arrest. Because catecholamine administration is directly contraindicated for patients with CPVT, resuscitative and post-arrest care are unique. These patients tend to be previously healthy, with normal resting electrocardiograms and no cardiac structural abnormalities, making diagnosis quite challenging.