Медицинская библиотека · Frontiers in cardiovascular medicine · 2026

Impact of age on the management and prognosis of esophageal fistula after atrial fibrillation ablation-a subanalysis of the worldwide POTTER-AF study.

Popescu Sorin S, Demirtakan Zeynep G, Schmidt Vanessa, Pürerfellner Helmut, Sommer Philipp, Sohns Christian, Veltmann Christian, Steven Daniel, Chun K R Julian, Maury Philippe, Gandjbakhch Estelle, Laredo Mikael, Willems Stephan, Beiert Thomas, Iden Leon, Füting Anna, Spittler Raphael, Richter Sergio, Schade Anja, Kuniss Malte, Wunderlich Carsten, Shin Dong-In, Grosse Meininghaus Dirk, Bonsels Marc, Reek David, Wiegand Uwe, Bauer Alexander, Metzner Andreas, Eckardt Lars, Krahnefeld Olaf, Sticherling Christian, Kühne Michael, Nguyen Dinh Quang, Roten Laurent, Linz Dominik, van der Voort Pepijn, Mulder Bart A, Vijgen Johan, Almorad Alexandre, Guenancia Charles, Fauchier Laurent, Boveda Serge, De Greef Yves, Da Costa Antoine, Jais Pierre, Milhem Antoine, Jesel Laurence, Garcia Rodrigue, Poty Hervé, Khoueiry Ziad, Seitz Julien, Laborderie Julien, Mechulan Alexis, Brigadeau Francois, Zhao Alexandre, Saludas Yannick, Piot Olivier, Ahluwalia Nikhil, Martin Claire, Chen Jian, Antolic Bor, Leventopoulos Georgios, Özcan Emin Evren, Yorgun Hikmet, Cay Serkan, Yalin Kivanc, Sobhy Botros Maichel, Jędrzejczyk-Patej Ewa, Inaba Osamu, Okumura Ken, Ejima Koichiro, Khakpour Houman, Catanzaro John N, Reddy Vivek, Natale Andrea, Blessberger Hermann, Yang Bing, Vogler Julia, Kuck Karl-Heinz, Merino José Luis, Keelani Ahmad, Heeger Christian-H, Tilz Roland Richard

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Аннотация

BACKGROUND

Esophageal fistula (EF) is a rare but devastating complication following atrial fibrillation (AF) ablation. Data regarding the impact of age on EF are scarce.

OBJECTIVE

To study the impact of age on the management and prognosis of EF following catheter ablation for AF.

METHODS

The POTTER-AF study is a worldwide registry on EF following catheter ablation for AF. A total of 553,729 patients underwent AF ablation in 214 centers between 1996 and 2022. Of them, 138 patients experienced EF, and data regarding age, management, and prognosis were available in 113 patients. The population was divided based on the median age.

RESULTS

The median age was 63 years; 54 patients were <63 years old (Group 1), and 59 patients were ≥63 years old (Group 2). The groups were similar regarding procedural characteristics. The older population had a shorter time to symptom onset [15.0 (6.0, 21.0) vs. 21.0 (10.0, 25.3) days; p = 0.031]. Group 2 was less likely to receive a brain CT or MRI for diagnosis (25.9% vs. 45.3%; p = 0.046). The older population was more likely to undergo endoscopic treatment without surgery (27.6% vs. 11.3%; p = 0.035). Conservative and surgical treatments were used in similar proportions. A trend toward higher fatality was noted in the older patients (72.9% vs. 56.6%; p = 0.078).

CONCLUSION

The older population had a shorter time to symptom onset, was less likely to receive a brain CT or MRI, and more likely to be treated by an endoscopic approach only. The older patient group showed a trend toward a higher fatality.

Для цитирования: Popescu Sorin S, Demirtakan Zeynep G, Schmidt Vanessa, Pürerfellner Helmut, Sommer Philipp, Sohns Christian, Veltmann Christian, Steven Daniel, Chun K R Julian, Maury Philippe, Gandjbakhch Estelle, Laredo Mikael, Willems Stephan, Beiert Thomas, Iden Leon, Füting Anna, Spittler Raphael, Richter Sergio, Schade Anja, Kuniss Malte, Wunderlich Carsten, Shin Dong-In, Grosse Meininghaus Dirk, Bonsels Marc, Reek David, Wiegand Uwe, Bauer Alexander, Metzner Andreas, Eckardt Lars, Krahnefeld Olaf, Sticherling Christian, Kühne Michael, Nguyen Dinh Quang, Roten Laurent, Linz Dominik, van der Voort Pepijn, Mulder Bart A, Vijgen Johan, Almorad Alexandre, Guenancia Charles, Fauchier Laurent, Boveda Serge, De Greef Yves, Da Costa Antoine, Jais Pierre, Milhem Antoine, Jesel Laurence, Garcia Rodrigue, Poty Hervé, Khoueiry Ziad, Seitz Julien, Laborderie Julien, Mechulan Alexis, Brigadeau Francois, Zhao Alexandre, Saludas Yannick, Piot Olivier, Ahluwalia Nikhil, Martin Claire, Chen Jian, Antolic Bor, Leventopoulos Georgios, Özcan Emin Evren, Yorgun Hikmet, Cay Serkan, Yalin Kivanc, Sobhy Botros Maichel, Jędrzejczyk-Patej Ewa, Inaba Osamu, Okumura Ken, Ejima Koichiro, Khakpour Houman, Catanzaro John N, Reddy Vivek, Natale Andrea, Blessberger Hermann, Yang Bing, Vogler Julia, Kuck Karl-Heinz, Merino José Luis, Keelani Ahmad, Heeger Christian-H, Tilz Roland Richard. Impact of age on the management and prognosis of esophageal fistula after atrial fibrillation ablation-a subanalysis of the worldwide POTTER-AF study.. Frontiers in cardiovascular medicine. 2026. DOI: 10.3389/fcvm.2025.1708499.

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