[Aike mixture has good anti-inflammatory and analgesic effects on mice].

OBJECTIVE

To study the anti-inflammatory and analgesic actions of Aike Mixture (AKM).

METHODS

A total of 100 male mice were randomly assigned into 5 groups: a normal control group, a drug control group (a hydrocortisone subgroup and an atropine subgroup), a high-dose AKM group, a mid-dose AKM group and a low-dose AKM group. Xylene was spread on the left ear of the experimental mice to induce inflammation, and 1% acetic acid solution injected into the abdominal cavity to produce pain so as to cause the body bend. Different doses of AKM were given and their actions observed.

RESULTS

AKM had obvious anti-inflammatory effect on the xylene-induced ear tumefaction and inhibited the pain-caused body bend in the AKM groups, with significant difference from the normal control (P < 0.01).

CONCLUSION

AKM has good anti-inflammatory and analgesic effects, which is of clinical significance in the treatment of chronic prostatitis.