Journal of perinatology : official journal of the California Perinatal Association · 2026
Maternal neighborhood deprivation and its association with early childhood neurodevelopmental impairment in extremely preterm infants.
СтатьяНазвание и аннотация: Перевод в очереди
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Brackett Cherise, Diggs Stephanie, Letzkus Lisa, Gummadi Angela, Travers Colm P, Benz Rachel, Vesoulis Zachary, Duncan Amanda, Sahni Rakesh, Ambalavanan N, Fairchild Karen, Chernyavskiy Pavel, Sullivan Brynne
Аннотация
OBJECTIVE: Evaluate whether maternal Area Deprivation Index (ADI) is associated with neurodevelopmental impairment (NDI) at age 2 in extremely preterm infants.
STUDY DESIGN: Retrospective cohort study of infants <29 weeks' gestation at four NICUs spanning multiple US regions. We analyzed the relationship between ADI and NDI, defined as no/mild, moderate, or severe based on the lowest component score on the Bayley Scales of Infant and Toddler Development exam, using a Bayesian ordinal cumulative logit hurdle model. Adjustments included sex, birthweight, maternal race/ethnicity, outborn, severe intraventricular hemorrhage, and late-onset sepsis or necrotizing enterocolitis.
RESULTS: Of 1278 infants studied, 275 underwent a Bayley exam. Lower birthweight, male sex, and inborn status were associated with undergoing a Bayley exam. Higher ADI, lower birthweight, male sex, and late-onset sepsis were linked to more severe NDI. ADI was independently associated with NDI risk.
CONCLUSION: Maternal deprivation measured by ADI was associated with NDI risk.
STUDY DESIGN: Retrospective cohort study of infants <29 weeks' gestation at four NICUs spanning multiple US regions. We analyzed the relationship between ADI and NDI, defined as no/mild, moderate, or severe based on the lowest component score on the Bayley Scales of Infant and Toddler Development exam, using a Bayesian ordinal cumulative logit hurdle model. Adjustments included sex, birthweight, maternal race/ethnicity, outborn, severe intraventricular hemorrhage, and late-onset sepsis or necrotizing enterocolitis.
RESULTS: Of 1278 infants studied, 275 underwent a Bayley exam. Lower birthweight, male sex, and inborn status were associated with undergoing a Bayley exam. Higher ADI, lower birthweight, male sex, and late-onset sepsis were linked to more severe NDI. ADI was independently associated with NDI risk.
CONCLUSION: Maternal deprivation measured by ADI was associated with NDI risk.