The Israel Medical Association journal : IMAJ · 2008
Onychomycosis: rationalization of topical treatment.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Shemer Avner, Trau Henri, Davidovici Batya, Amichai Boaz, Grunwald Marcelo H
Аннотация
BACKGROUND: Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population.
OBJECTIVES: To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis.
METHODS: We evaluated 331 patients with suspected clinical toenail onychomycosis affecting at least two toenails. Mycological examination of the affected nails was performed; both the KOH test and fungal culture were used.
RESULTS: Of 331 patients with suspected clinical toenail onychomycosis, 78.2% of the patients had at least three infected nails. The first toenail was the most affected. Trichophyton rubrum was by far the most common dermatophyte cultured from all samples.
CONCLUSIONS: Most of the patients had at least three affected toenails. Topical treatment is not effective or practical, and systemic treatment should therefore be considered.
OBJECTIVES: To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis.
METHODS: We evaluated 331 patients with suspected clinical toenail onychomycosis affecting at least two toenails. Mycological examination of the affected nails was performed; both the KOH test and fungal culture were used.
RESULTS: Of 331 patients with suspected clinical toenail onychomycosis, 78.2% of the patients had at least three infected nails. The first toenail was the most affected. Trichophyton rubrum was by far the most common dermatophyte cultured from all samples.
CONCLUSIONS: Most of the patients had at least three affected toenails. Topical treatment is not effective or practical, and systemic treatment should therefore be considered.