Ischemia-Modified Albumin (IMA) levels in ectopic pregnancy and early pregnancy loss.

BACKGROUND

IMA is a novel marker to consider in ischemic conditions. The initial stages of pregnancy represent a physiological ischemic status. IMA levels may be changed when there is suspicion of early pregnancy complications because of increased oxidative stress.

AIM: We aimed to determine and compare IMA values in cases of ectopic and healthy pregnancies as well as early pregnancy loss.

METHODS

This prospective case control study population (n = 91) consisted of early pregnancy loss (n = 28), ectopic pregnancy (n = 28), and an intracavitary early healthy pregnancy (n = 35). The serum IMA levels were compared in these groups.

RESULTS

Demographic parameters were similar and there was no significant difference between the three groups in terms of serum IMA concentrations.

CONCLUSION

We suggested that IMA cannot be used clinically for the diagnosis and follow up of early pregnancy complications during the first five to six gestational weeks.