Timing of the Arterial Switch Operation in Premature Neonates < 2 kg With d-Loop Transposition of the Great Arteries and Intact Ventricular Septum-A Case Series.

There is a paucity of data available regarding operative timing and approach for d-loop transposition of the great arteries (dTGA) with intact ventricular septum (IVS) in premature infants. We reviewed our surgical experience in a case series of five premature infants (<37 weeks gestational age) with dTGA/IVS and birthweights <2.0 kg. All five infants underwent primary arterial switch operation (ASO) at a median postnatal age of 19 days and weight of 1.8 kg. None of the infants had major postsurgical complications or needed reoperation. All infants were discharged home on room air. We demonstrated that premature infants <2.0 kg with dTGA/IVS can successfully undergo the ASO at <3 weeks postnatal age with no significant cardiac or neonatal complications.