Effects of dyclonine mucilage and compound lidocaine cream as tracheal catheter lubricant on postoperative pharyngeal complications after general anesthesia.

BACKGROUND

The aim of this study was to observe the effects of dyclonine mucilage and compound lidocaine cream on postoperative pharyngeal complications after general anesthesia.

METHODS

Ninety patients were randomly divided into a dyclonine mucilage group (D group), a compound lidocaine cream group (L group), and a normal saline group (NS group). The primary outcomes were the incidence and severity of postoperative sore throat (POST). The secondary outcomes were postoperative cough (POC), hoarseness of voice (HOV), and the incidence of foreign body sensation (FBS) in the pharynx at 1, 6, and 24 hours after surgery.

RESULTS

The incidence of POST at 1 and 6 hours after surgery in the L group was significantly lower than that in the D group ( P = 0.015 and 0.012, respectively). There was no difference in the incidence of POC and HOV at 1, 6, and 24 hours after surgery between the D and L groups ( PPOC  = 0.267, 0.236, 0.335, and PHOV  = 0.500, 0.353, and 0.306, respectively). The severity scores of POST, POC, and HOV were significantly lower in the L groups than in the NS group at 1 and 6 hours after surgery ( P < 0.001, P < 0.001, P < 0.001,  P = 0.001, 0.011, and 0.005, respectively). The incidence of pharyngeal FBS in the D group was significantly greater than that in the NS group at 1 hour after surgery ( P =  0.012). The postoperative satisfaction scores in the L group were significantly greater than those in the D group ( P = 0.007 and  P = 0.009).

CONCLUSION

Compared with dyclonine mucilage, compound lidocaine cream was associated with a lower incidence of early POST and higher postoperative satisfaction, with no increase in the incidence of pharyngeal FBS.