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DOI 10.1016/j.dsx.2016.03.012

Медицинская библиотека · Diabetes & metabolic syndrome · 2016

Serum C1q and tumor necrosis factor (TNF)-related protein 9 in women with Polycystic Ovary Syndrome.

Forouhi Neda, Saedisomeolia Ahmad, Djalali Mahmoud, Eshraghian Mohammad Reza, Morshedzadeh Nava, Zabetian-Targhi Fateme, Mahmoudi Maryam

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Аннотация

AIMS: To compare CTRP9 levels in women with Polycystic Ovary Syndrome (PCOS) and without PCOS. Furthermore, to determine the correlation between serum CTRP9 levels and some variety of anthropometric and biochemical parameters.

METHODS

The study included 29 PCOS patients and 27 healthy volunteers of the same age and BMI. Body weight, height and waist circumference were assessed. Blood samples were taken for assessment of serum CTRP9 by enzyme-linked immunosorbent assay (ELISA) technique. In addition, blood samples were collected for fasting insulin, glucose, and lipid profiles, and homeostasis model of assessment-insulin resistance (HOMA-IR) values were calculated.

RESULTS

Similar serum CTRP9 were found in PCOS subjects and controls (8.8±19.9 vs 5.0±7.6ng/mL). Serum CTRP9 concentration positively correlated with serum LDL-C and total cholesterol in patient group. However, no correlation between CTRP9 and other biochemical and anthropometric variables was found.

CONCLUSION

Serum CTRP9 logs of PCOS participants exhibit a positive association with unfavorable lipid profile in this report.

Для цитирования: Forouhi Neda, Saedisomeolia Ahmad, Djalali Mahmoud, Eshraghian Mohammad Reza, Morshedzadeh Nava, Zabetian-Targhi Fateme, Mahmoudi Maryam. Serum C1q and tumor necrosis factor (TNF)-related protein 9 in women with Polycystic Ovary Syndrome.. Diabetes & metabolic syndrome. 2016. DOI: 10.1016/j.dsx.2016.03.012.

Предметные рубрики MeSH

AdiponectinAdolescentAdultBlood GlucoseBody HeightBody Mass IndexBody WeightEnzyme-Linked Immunosorbent AssayFemaleGlycoproteinsHumansInsulinInsulin ResistanceLinear ModelsLipidsPolycystic Ovary SyndromeTumor Necrosis Factor Receptor-Associated Peptides and ProteinsWaist Circumference
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