Fertility and sterility · 2014
Impact of sperm morphology on the likelihood of pregnancy after intrauterine insemination.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Deveneau Nicolette E, Sinno Omar, Krause Miriam, Eastwood Daniel, Sandlow Jay I, Robb Paul, Granlund Amy, Strawn Estil Y
Аннотация
OBJECTIVE: To determine whether there is a difference in ongoing pregnancy rates (PRs) between patients undergoing IUI with strict sperm morphology ≤4% compared with >4% on initial semen analysis.
DESIGN: Retrospective chart review with multivariate analysis.
SETTING: Academic outpatient reproductive center.
PATIENT(S): A total of 408 couples with male and/or female factor infertility and known strict sperm morphology (SSM).
INTERVENTION(S): A total of 856 IUIs with partner's sperm (IUI-P).
MAIN OUTCOME MEASURE(S): Ongoing PRs based on ultrasound documentation of intrauterine pregnancy with fetal heart tones.
RESULT(S): There is no statistically significant difference in per cycle PRs when comparing patients with a strict sperm morphology of ≤4% versus >4% who undergo IUI-P (17.3% vs. 16.7%; odds ratio 0.954, 95% confidence interval 0.66-1.37). Multiple potential confounding factors were assessed using multivariate analysis.
CONCLUSION(S): Strict sperm morphology ≤4% is not associated with lower PRs in couples undergoing IUI-P, and thus should not be the sole reason for advancing to IVF.
DESIGN: Retrospective chart review with multivariate analysis.
SETTING: Academic outpatient reproductive center.
PATIENT(S): A total of 408 couples with male and/or female factor infertility and known strict sperm morphology (SSM).
INTERVENTION(S): A total of 856 IUIs with partner's sperm (IUI-P).
MAIN OUTCOME MEASURE(S): Ongoing PRs based on ultrasound documentation of intrauterine pregnancy with fetal heart tones.
RESULT(S): There is no statistically significant difference in per cycle PRs when comparing patients with a strict sperm morphology of ≤4% versus >4% who undergo IUI-P (17.3% vs. 16.7%; odds ratio 0.954, 95% confidence interval 0.66-1.37). Multiple potential confounding factors were assessed using multivariate analysis.
CONCLUSION(S): Strict sperm morphology ≤4% is not associated with lower PRs in couples undergoing IUI-P, and thus should not be the sole reason for advancing to IVF.