Egyptian consensus guidance for diagnosis of adults with non-infectious uveitis.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Fadel Mariam Raouf, Youssef Maha Mohamed, Salem Noha Osama, Noureldin Omneya Ashraf, Soliman Mahmoud Mohamed, Amin Rana Hussein, Hassan Lameece Moustafa, Elzanaty Radwa Taher, Naga Shereen Hassan Aboul, Elmohsen Mai Nasser Abd, AbouelSaad Mohamed Refaat, Wassef Amr Mohamed Abdelaziz, El Nokrashy Amgad, Mohamed Noha Salah, Haroun Ibrahim Abuelmagd, Amin Hind, Samir Asmaa Mohamad, Shoughy Samir, Azim Mohamed Abdel, Radwan Alaa, El-Ghobashy Nehal, Abu-Zaid Mohammed Hassan, Maged Lobna A, El Garf Ayman, Eldesouky Aya Tallah Haris Ibrahim, Mohamed Sally Samy, Elziaty Rahma A, Karim Marwa A, Attia Omnia B, El-Rahman Walaa Abd, Teleb Doaa Ahmed, Ashour Doaa Maamoun
Аннотация
METHODS: A modified three-round Delphi process was conducted from January to May 2024. A multidisciplinary committee of uveitis specialists, rheumatologists, and internists formulated 24 statements across eight diagnostic domains. Experts ranked statements using a 5-point Likert scale, with consensus defined as ≥ 75% agreement, a median score ≥ 4, and an interquartile range (IQR) ≤ 1.
RESULTS: A total of 26 experts participated in the first round, with 21 and 18 experts completing the second and third rounds, respectively (69.2% overall retention). The panel achieved consensus on all 24 diagnostic statements, emphasizing standardized examination and SUN-based inflammation grading. The panel endorsed a stepwise cost-effective systemic workup, mandating the exclusion of tuberculosis and syphilis in all adults and utilizing chest imaging (CXR/HRCT) as a baseline. MRI brain/orbit with gadolinium contrast was advised for selected cases. OCT and fluorescein angiography were recommended baseline imaging for posterior and panuveitis, while ocular sampling (aqueous or vitreous) was reserved for atypical or resistant cases. Disease description should follow SUN anatomical classification, and sight-threatening uveitis was defined by severe or prolonged inflammation that could permanently affect vision.
CONCLUSIONS: This multidisciplinary consensus provides a structured, evidence-driven framework for uveitis diagnosis tailored to the Egyptian clinical and epidemiological context. It aims to standardize local practice while aligning with international standards. Broader applicability requires local adaptation and validation.