Plasma exchange in rhabdomyolysis.

The effect of plasma exchange (PE) was evaluated in 4 patients with rhabdomyolysis. A single 21 PE produced a transient fall of creatinine phosphokinase and did not prevent renal failure. Theoretically PE would need to be performed very frequently to remove toxins in appropriate amounts. Since renal failure in myoglobinuira has a relative good prognosis, we do not recommend intensive PE as therapy.