Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2019
[Mast cell activation syndrome. About a clinical case].
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Cardona Ricardo, Muñoz-Ávila Maria Angélica, Gómez-Henao Catalina, Diez-Zuluaga Susana, Gálvez-Cárdenas Kenny Mauricio
Аннотация
BACKGROUND: Monoclonal mast cell activation syndrome is included in mast cell activation disorders in which, after a diagnostic process, it is not possible to meet the required criteria for a diagnosis of systemic mastocytosis.
CLINICAL CASE: A 73-year-old woman who presented two events of anaphylaxis 15 minutes after the intake of yucca; with a positive skin test, elevated tryptase, and mast cells with abnormal phenotype in the bone marrow biopsy, and without criteria for systemic mastocytosis.
CONCLUSION: The diagnosis of monoclonal mast cell activation syndrome requires high clinical suspicion for patients with recurrent anaphylaxis and elevated tryptase, for whom joint management with hematology is essential.
CLINICAL CASE: A 73-year-old woman who presented two events of anaphylaxis 15 minutes after the intake of yucca; with a positive skin test, elevated tryptase, and mast cells with abnormal phenotype in the bone marrow biopsy, and without criteria for systemic mastocytosis.
CONCLUSION: The diagnosis of monoclonal mast cell activation syndrome requires high clinical suspicion for patients with recurrent anaphylaxis and elevated tryptase, for whom joint management with hematology is essential.