Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2007
[Lithium and bipolar disorder--a renaissance?].
Аннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Simhandl Christian, Mersch Jens
Аннотация
OBJECTIVE: Overview and discussion regarding the use and relevance of lithium as an therapeutic agent for bipolar disorder in general, with a special focus on pregnancy, suicidality and possible side-effects.
METHOD: Literature was handsearched and by searches of medline with special interest in recent results and comparative studies.
RESULTS: Lithium is still of high importance in the treatment of bipolar disorder. It is unmatched regarding decades of clinical experience and scientific evidence. It has a proven efficacy in every spectrum of bipolar illness, with less profound data regarding acute bipolar depression. Especially long term treatment of bipolar patients with lithium shows clear clinical benefits i.e.: importance of a continuous setting, gain of mood stabilizing effect over time, no loss of efficacy, reduced morbidity and mortality.
DISCUSSION: Lithium should be regarded as a first line treatment for bipolar disorder.
METHOD: Literature was handsearched and by searches of medline with special interest in recent results and comparative studies.
RESULTS: Lithium is still of high importance in the treatment of bipolar disorder. It is unmatched regarding decades of clinical experience and scientific evidence. It has a proven efficacy in every spectrum of bipolar illness, with less profound data regarding acute bipolar depression. Especially long term treatment of bipolar patients with lithium shows clear clinical benefits i.e.: importance of a continuous setting, gain of mood stabilizing effect over time, no loss of efficacy, reduced morbidity and mortality.
DISCUSSION: Lithium should be regarded as a first line treatment for bipolar disorder.