Zhonghua yi xue za zhi · 2006
[Detection of 16S ribosomal RNA gene of bacteria in prostate tissues of adults].
Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Xie Hui, Huang Hui-cong, Yang Yi-rong, Wu Jian-bo, He Qiu-xiang, Zhu Qi-jian, Chen Jian-ou, Wang Si-qi, Li Cheng-di, Xia Peng, Shen Long-jie
Аннотация
OBJECTIVE: To investigate the role of bacteria in chronic prostatitis.
METHODS: Complete specimens of prostate were obtained from 140 organ donors, aged 20 - 35, at autopsy. A piece of tissue was collected from the peripheral zone of prostate from each specimen and was divided into 2 parts to undergo pathological examination and PCR so as to detect the 16S ribosomal RNA (16S rRNA) gene of bacteria.
RESULTS: Focal mild inflammation was shown in 46 of the 104 specimens (32.9%), including interstitial inflammation in 42 specimens, inflammation in both interstitial and body of gland in 3 specimens, and perigladulitis in 1 specimen. Twenty-seven of the 140 specimens (19.3%) were positive in 16S rRNA gene. The positive rate of 16S rRNA gene of the specimens with prostatitis was 48.9%, significantly higher than that of the specimens without prostatitis (5.3%, P < 0.001).
CONCLUSION: Bacteria may play an important role in the pathogenesis of chronic prostatitis.
METHODS: Complete specimens of prostate were obtained from 140 organ donors, aged 20 - 35, at autopsy. A piece of tissue was collected from the peripheral zone of prostate from each specimen and was divided into 2 parts to undergo pathological examination and PCR so as to detect the 16S ribosomal RNA (16S rRNA) gene of bacteria.
RESULTS: Focal mild inflammation was shown in 46 of the 104 specimens (32.9%), including interstitial inflammation in 42 specimens, inflammation in both interstitial and body of gland in 3 specimens, and perigladulitis in 1 specimen. Twenty-seven of the 140 specimens (19.3%) were positive in 16S rRNA gene. The positive rate of 16S rRNA gene of the specimens with prostatitis was 48.9%, significantly higher than that of the specimens without prostatitis (5.3%, P < 0.001).
CONCLUSION: Bacteria may play an important role in the pathogenesis of chronic prostatitis.