Journal of tropical medicine · 2025
Seroprevalence and Risk Factors of Transfusion-Related Infections Among Blood Donors in Central China During and After the COVID-19 Pandemic: Evaluation of TTIs in Shiyan.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Zhu Daiqian, Jiao Danmei, Tian Fang, Lv Ming, Zhang Yao, Xing Hao, Li Yufeng, Wei Shengnan, Li Jian
Аннотация
OBJECTIVE: Bloodborne pathogens including hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and Treponema pallidum pose a significant menace to transfusion medicine and the public health system. Conducted during the unprecedented global COVID-19 pandemic, this retrospective analysis (2020-2024) evaluated blood donors from Shiyan, China, aiming to ensure blood safety amidst the challenges posed by the pandemic.
METHODS: Cases of transfusion-transmitted infections (TTIs) were analyzed by using ELISA. Infection rates were quantified as stratified percentages based on sociodemographic characteristics of the study population. Chi-square trend tests were performed to examine the variation in trends. The chi-square test was performed to evaluate associations between sociodemographic characteristics (age, gender, and occupation) and the risk of pathogen infection (HBV, HCV, HIV, and T. pallidum).
RESULTS: Analysis of 231,733 blood samples from 114,593 donors revealed an overall 0.51% seropositivity for TTIs, with prevalence rates of HBV (0.23%), HCV (0.03%), HIV (0.03%), and syphilis (0.22%). During the COVID-19 pandemic, a declining trend was observed for all infections. The chi-square test disclosed that HBV and T. pallidum infection were higher in the other occupation group of women aged 35-60 years, HCV positivity was more pronounced in men in the same group, and HIV infection was mainly concentrated in the group of men aged 25-44 years.
CONCLUSIONS: Continuous monitoring of the prevalence of TTIs among blood donors offers valuable information for ensuring blood safety and new directions in the development of blood transfusion systems.
METHODS: Cases of transfusion-transmitted infections (TTIs) were analyzed by using ELISA. Infection rates were quantified as stratified percentages based on sociodemographic characteristics of the study population. Chi-square trend tests were performed to examine the variation in trends. The chi-square test was performed to evaluate associations between sociodemographic characteristics (age, gender, and occupation) and the risk of pathogen infection (HBV, HCV, HIV, and T. pallidum).
RESULTS: Analysis of 231,733 blood samples from 114,593 donors revealed an overall 0.51% seropositivity for TTIs, with prevalence rates of HBV (0.23%), HCV (0.03%), HIV (0.03%), and syphilis (0.22%). During the COVID-19 pandemic, a declining trend was observed for all infections. The chi-square test disclosed that HBV and T. pallidum infection were higher in the other occupation group of women aged 35-60 years, HCV positivity was more pronounced in men in the same group, and HIV infection was mainly concentrated in the group of men aged 25-44 years.
CONCLUSIONS: Continuous monitoring of the prevalence of TTIs among blood donors offers valuable information for ensuring blood safety and new directions in the development of blood transfusion systems.