JACC. Case reports · 2025
Syphilitic Aortitis Presenting With De-Novo Aortic Thrombus and Acute Myocardial Infarction.
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Mendez Richard S, Mohamoud Abdilahi, Abdelhamid Mahmoud Omar Atef, Park Byoung Uk, Polycarpou Andreas, Punjabi Gopal, Shroff Gautam R, Shaffer Andrew W
Аннотация
BACKGROUND: Syphilitic aortitis, caused by Treponema pallidum, is a known complication of tertiary or latent syphilis.
CASE SUMMARY: We present a case of syphilitic aortitis in a patient who presented with acute inferior ST-segment elevation myocardial infarction and was detected to have a large, mobile aortic thrombus on cardiac magnetic resonance imaging and confirmed with coronary computed tomography angiogram. After multidisciplinary discussion, the patient underwent urgent definitive surgical intervention.
DISCUSSION: With syphilis cases surging, clinicians must maintain a high index of suspicion for syphilitic aortitis with atypical clinical presentations. Multimodality cardiovascular imaging is imperative to establish a diagnosis, and surgical intervention may be required to treat this rare disease.
TAKE-HOME MESSAGE: Awareness and timely intervention are essential to address this morbid, re-emerging public health challenge.
CASE SUMMARY: We present a case of syphilitic aortitis in a patient who presented with acute inferior ST-segment elevation myocardial infarction and was detected to have a large, mobile aortic thrombus on cardiac magnetic resonance imaging and confirmed with coronary computed tomography angiogram. After multidisciplinary discussion, the patient underwent urgent definitive surgical intervention.
DISCUSSION: With syphilis cases surging, clinicians must maintain a high index of suspicion for syphilitic aortitis with atypical clinical presentations. Multimodality cardiovascular imaging is imperative to establish a diagnosis, and surgical intervention may be required to treat this rare disease.
TAKE-HOME MESSAGE: Awareness and timely intervention are essential to address this morbid, re-emerging public health challenge.