Sage open pediatrics · 2026
Incidence of Neonatal Meningitis and the Premature Mortality in Eastern Sub-saharan Africa, From 1990 to 2023: A Global Burden of Diseases Study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tadesse Sebsibe, Gemechu Tibeso, Lemma Kebebew, Alemseged Embay Amare, Lomboro Dimore Abraham, Amare Hiwot Hailu, Bedewi Jemal, Tessema Zufan, Mersha Abera, Tesfau Yemane Berhane, Welesemayat Embaba Tekelaye, Safayi Boko Loka, Aliyo Alqeer, Negesa Beyene Belda, Ashenafi Girma, Dube Geleta Nenko, Jofa Beka Yambo, Fikrie Anteneh
Аннотация
OBJECTIVE: Quantify neonatal meningitis incidence and years of life lost (YLLs) in Eastern Sub-Saharan Africa (ESSA) from 1990 to 2023.
METHODS: Secondary analysis of GBD data analyzed temporal trends by location, year and sex. Bayesian meta-regression estimated incidence, cause of death ensemble modeling calculated YLLs, and spatiotemporal Gaussian process regression smoothed trends. Estimates include 95% uncertainty intervals (UIs).
RESULTS: In 2023, ESSA's neonatal meningitis incidence rate was 2,542 per 100,000 (95% UI: 2,043-3,065), heavily concentrated in early neonates (5,415) versus late neonates (1,574). The regional YLL rate was 24,855 per 100,000, driven by early neonates (66,882). Somalia and South Sudan exceeded regional averages. Globally, YLL rates declined from 1990 to 2023 (Annual Rate of Change: -0.70%).
CONCLUSION: ESSA faces a severe neonatal meningitis burden skewed toward early neonates. Urgent strategies must scale up maternal screening, intrapartum antibiotics, and rapid diagnostics for fast-tracked treatment.
METHODS: Secondary analysis of GBD data analyzed temporal trends by location, year and sex. Bayesian meta-regression estimated incidence, cause of death ensemble modeling calculated YLLs, and spatiotemporal Gaussian process regression smoothed trends. Estimates include 95% uncertainty intervals (UIs).
RESULTS: In 2023, ESSA's neonatal meningitis incidence rate was 2,542 per 100,000 (95% UI: 2,043-3,065), heavily concentrated in early neonates (5,415) versus late neonates (1,574). The regional YLL rate was 24,855 per 100,000, driven by early neonates (66,882). Somalia and South Sudan exceeded regional averages. Globally, YLL rates declined from 1990 to 2023 (Annual Rate of Change: -0.70%).
CONCLUSION: ESSA faces a severe neonatal meningitis burden skewed toward early neonates. Urgent strategies must scale up maternal screening, intrapartum antibiotics, and rapid diagnostics for fast-tracked treatment.