Medicine · 2025
Concurrent hepatitis and anterior uveitis in an immunocompetent patient with secondary syphilis: A case report.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Kheir Hamed, Elazab Emad, Hassan Haytham, Kassab Mohamed, Hajjat Sufyan, Makin Mohammed, Hamad Abubakr, Ahmad Nehad Jaser
Аннотация
RATIONALE: Syphilis, a sexually transmitted infection caused by Treponema pallidum, is primarily spread through sexual contact and can lead to severe systemic complications if untreated.
PATIENT CONCERNS: A 42-year-old immunocompetent male presented with a nonpruritic papulosquamous rash sparing the palms and soles, which progressed to anterior uveitis and hepatitis.
DIAGNOSES: Diagnosis was confirmed by positive rapid plasma reagin and T pallidum hemagglutination assay, alongside histopathological evidence of granulomatous hepatitis on liver biopsy and slit-lamp findings consistent with anterior uveitis.
INTERVENTIONS: The patient was hospitalized and treated with intravenous aqueous penicillin G (3 million units every 4 hours for 14 days).
OUTCOMES: To our knowledge, this represents the first reported case in Saudi Arabia of secondary syphilis manifesting concurrently with anterior uveitis and hepatitis in an immunocompetent host.
LESSONS: The study underscores the importance of considering syphilis in atypical presentations to ensure timely diagnosis and management.
PATIENT CONCERNS: A 42-year-old immunocompetent male presented with a nonpruritic papulosquamous rash sparing the palms and soles, which progressed to anterior uveitis and hepatitis.
DIAGNOSES: Diagnosis was confirmed by positive rapid plasma reagin and T pallidum hemagglutination assay, alongside histopathological evidence of granulomatous hepatitis on liver biopsy and slit-lamp findings consistent with anterior uveitis.
INTERVENTIONS: The patient was hospitalized and treated with intravenous aqueous penicillin G (3 million units every 4 hours for 14 days).
OUTCOMES: To our knowledge, this represents the first reported case in Saudi Arabia of secondary syphilis manifesting concurrently with anterior uveitis and hepatitis in an immunocompetent host.
LESSONS: The study underscores the importance of considering syphilis in atypical presentations to ensure timely diagnosis and management.