Clinical laboratory · 2025
Does Syphilis need to be Examined in Cases of Blood and Body Fluid Exposure in Hospitals?
Письмо в редакциюНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hagiya Hideharu
Аннотация
BACKGROUND: Syphilis, caused by Treponema pallidum, represents a significant sexually transmitted infection capable of systemic manifestation. Current guidelines do not recommend syphilis serological screening following blood and body fluid exposure (BBFE) in healthcare settings. This cross-sectional study examined current practices of rapid plasma reagin (RPR) and T. pallidum hemagglutination (TPHA) testing in Japanese hospitals.
METHODS: A web-based questionnaire distributed in November 2023 assessed institutional testing policies and post-exposure protocols.
RESULTS: Among 23 responding institutions, preoperative screening included both RPR and TPHA in nine hospitals (39%) and TPHA alone in seven (31%). For non-preoperative screening, five hospitals (22%) conducted both tests, while six (26%) performed TPHA only. No consensus existed regarding test validity duration, and only one hospital maintained post-exposure prophylaxis protocols.
CONCLUSIONS: Although approximately 75% of institutions conduct routine preoperative syphilis screening, the lack of evidence supporting BBFE transmission and prophylaxis necessitates practice reconsideration.
METHODS: A web-based questionnaire distributed in November 2023 assessed institutional testing policies and post-exposure protocols.
RESULTS: Among 23 responding institutions, preoperative screening included both RPR and TPHA in nine hospitals (39%) and TPHA alone in seven (31%). For non-preoperative screening, five hospitals (22%) conducted both tests, while six (26%) performed TPHA only. No consensus existed regarding test validity duration, and only one hospital maintained post-exposure prophylaxis protocols.
CONCLUSIONS: Although approximately 75% of institutions conduct routine preoperative syphilis screening, the lack of evidence supporting BBFE transmission and prophylaxis necessitates practice reconsideration.