American journal of obstetrics and gynecology · 2008
Clinical presentation of hydatidiform mole in northern Italy: has it changed in the last 20 years?
Сравнительное исследованиеСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Mangili Giorgia, Garavaglia Elisabetta, Cavoretto Paolo, Gentile Cinzia, Scarfone Giovanna, Rabaiotti Emanuela
Аннотация
OBJECTIVE: This study was undertaken to evaluate whether the current clinical presentation of hydatidiform mole changed in the recent years compared with an historic group.
STUDY DESIGN: We retrieved 500 patients from our database. We compared the clinical presentation of 189 cases followed-up between 1992-2004 ("later" group) with that of a previous series of 311 patients ("earlier" group, 1970-1982). A Pearson chi2 test was performed analyzing the following variables: uterine volume, ovarian cysts, vaginal bleeding, hyperemesis, preeclampsia, and maternal age; we considered P < .05 to be significant.
RESULTS: Uterine volume corrected for gestational age (P < .0001), vaginal bleeding (P < .0001) and presence of ovarian cysts (P = .03) were significantly predominant in the "earlier" group, whereas the incidence of preeclampsia and hyperemesis were not significantly different.
CONCLUSIONS: The depiction of increased uterine volume, ovarian theca lutein cysts, and vaginal bleeding in hydatidiform mole at presentation is significantly less frequent since the extensive dissemination of ultrasound in obstetrics.
STUDY DESIGN: We retrieved 500 patients from our database. We compared the clinical presentation of 189 cases followed-up between 1992-2004 ("later" group) with that of a previous series of 311 patients ("earlier" group, 1970-1982). A Pearson chi2 test was performed analyzing the following variables: uterine volume, ovarian cysts, vaginal bleeding, hyperemesis, preeclampsia, and maternal age; we considered P < .05 to be significant.
RESULTS: Uterine volume corrected for gestational age (P < .0001), vaginal bleeding (P < .0001) and presence of ovarian cysts (P = .03) were significantly predominant in the "earlier" group, whereas the incidence of preeclampsia and hyperemesis were not significantly different.
CONCLUSIONS: The depiction of increased uterine volume, ovarian theca lutein cysts, and vaginal bleeding in hydatidiform mole at presentation is significantly less frequent since the extensive dissemination of ultrasound in obstetrics.