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Nutrition (Burbank, Los Angeles County, Calif.) · 2025

Acute-phase Geriatric Nutritional Risk Index is associated with swallowing function after convalescent rehabilitation in older patients with ischemic stroke: A retrospective cohort study.

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Moriyama Toshiyuki, Sato Fumio, Yokomichi Nobuyuki, Yamanaka Kei, Yoshikawa Yoji, Tachibana Masaki, Kuroda Junya, Tanaka Eri, Fukumoto Hironori, Nakane Hiroshi

Аннотация

INTRODUCTION: Post‑stroke dysphagia and malnutrition both compromise recovery. Whether the Geriatric Nutritional Risk Index (GNRI) measured on acute admission predicts swallowing function after convalescent rehabilitation remains unclear.

METHODS: This study retrospectively analyzed 254 with ischemic stroke patients aged ≥ 65 y (median age 79.3 y; 141 men) who were admitted within 7 d of stroke onset and subsequently transferred to convalescent rehabilitation hospitals. GNRI was calculated within 3 d of acute admission. Swallowing function was assessed with the Functional Oral Intake Scale (FOIS). Multivariate linear regression analyses with FOIS on convalescent discharge included acute-phase GNRI, age, sex, brainstem lesion, premorbid modified Rankin Scale, National Instituted of Health Stroke Scale, hemoglobin, C-reactive protein, Functional Independence Measure, days to speech therapy initiation, and baseline FOIS, which were assessed at the time of admission to the acute hospital.

RESULTS: Fifty-one (20.1%) had malnutrition for GNRI < 92 on acute admission. Patients with malnutrition were lower FOIS on acute admission (P = 0.002) and convalescent discharge (P < 0.001) than patients without malnutrition. Multivariate linear regression analyses revealed that acute-phase GNRI (β = 0.151; P = 0.019), premorbid modified Rankin Scale (β = -0.149; P = 0.009), C-reactive protein (β = 0.138; P = 0.024), days to speech therapy initiation (β = -0.116; P = 0.031), and baseline FOIS (β = 0.37; P < 0.001) were significantly associated with FOIS on convalescent discharge.

CONCLUSIONS: Acute‑phase GNRI may predict swallowing function after convalescent rehabilitation in older patients with ischemic stroke.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты