Cureus · 2025
Allgrove Syndrome in Adults: A Case of an Atypical Presentation.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Maizi Meryem, Belabbes Fatima, Delsa Hanane, Elamari Saloua, Ben Elbarhdadi Imane
Аннотация
Allgrove syndrome, or "Triple A" syndrome, is a rare autosomal recessive disorder characterized by achalasia, alacrima, and adrenal insufficiency. Typically diagnosed in childhood or adolescence, its adult presentation remains under-recognized and challenging. We report the case of a 29-year-old Moroccan woman with chronic dysphagia, who was ultimately diagnosed with Allgrove syndrome following the discovery of type 1 achalasia, primary adrenal insufficiency, and alacrima. The diagnosis was delayed, and symptoms had persisted for over a decade before appropriate evaluation. Clinical, endoscopic, radiologic, and manometric findings confirmed the diagnosis. Therapeutic management included corticosteroids and pneumatic dilation, with a favorable outcome. This case highlights the importance of considering Allgrove syndrome in adults with unexplained dysphagia and systemic symptoms.