Prevalence and risk factors evaluation for transfusion-transmissible infections among blood donors from Shiyan, China.

OBJECTIVE

Transfusion-transmissible infections (TTIs) are severe threats to blood safety and public health. A retrospective study of blood donor records from 2015 to 2019 in Shiyan, China, was conducted.

METHODS

TTI prevalence was analyzed using ELISA, RT-PCR, and demographic data. Chi-square test and logistic regression were used to analyze incidence trends and associations for HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema pallidum (T. pallidum).

RESULTS

Of 230,225 donors, 2,453 (1.07 %) were TTI-positive. HIV, HBV, HCV, syphilis rates were 0.08 %, 0.40 %, 0.19 %, 0.40 %. Significant decreases in HBV, HCV, T. pallidum from 2015 to 2019; HIV decreased from 2018 to 2019. The prevalence is higher among women aged 35-60, farmers with T. pallidum and young female students with HIV infection.

CONCLUSIONS

Despite the relatively low prevalence of TTIs at present, awareness of TTIs and ongoing blood screening are still needed to ensure blood safety.