Radiation-Induced Laryngeal Mucous Membrane Pemphigoid.

OBJECTIVES

Bullous pemphigoid has previously been linked to radiotherapy, but here we report the first case of MMP suspected to be a consequence of RT.

METHODS

The patient described is an 85-year-old male who underwent RT to treat squamous cell carcinoma of the palatine tonsil. Shortly after therapy, the patient developed blisters with worsening dyspnea and dysphonia.

RESULTS

This patient was successfully treated with a combination of oral immunosuppressants and surgical intervention.

CONCLUSION

This incident underscores that not all episodes of mucosal ulceration following radiation are a result of mucositis and MMP should be considered in the differential.

LEVEL OF EVIDENCE: Level 4.