Irish journal of medical science · 2026
Holmium laser lithotripsy and its effects on postoperative complications in urolithiasis.
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Cui Xinhao, Wu Zheng, Fan Xiaoqi
Аннотация
OBJECTIVE: This study investigated the impact of holmium laser lithotripsy on the incidence of postoperative complications in patients with urolithiasis.
METHODS: This study was a retrospective cohort study. A total of 115 patients diagnosed with urolithiasis and treated at our hospital were enrolled. According to the surgical procedure used, patients were assigned to a control group [n = 57, received extracorporeal shock wave lithotripsy (ESWL)], and a study group (n = 58, underwent holmium laser lithotripsy]. Baseline characteristics were compared. Postoperative complication rates, treatment efficacy, operative indicators (operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and hospital stay), and levels of inflammatory markers (C-reactive protein [CRP], procalcitonin [PCT]), and renal function indicators (serum creatinine [Scr]) were measured before surgery and one day postoperatively.
RESULTS: No significant differences were noted in baseline characteristics between the two groups (P > 0.05). The study group demonstrated a lower incidence of postoperative complications, a higher overall effective treatment rate, as well as lower operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and length of hospital stay (P < 0.05) relative to the control group. One day post-surgery, CRP, PCT, and Scr levels increased in both groups relative to preoperative values (P < 0.05), but the elevations were significantly lower in the study group (P < 0.05).
CONCLUSION: Holmium laser lithotripsy effectively decreases the incidence of postoperative complications in patients with urolithiasis, improves therapeutic outcomes, reduces surgical trauma, alleviates postoperative inflammatory responses, and mitigates renal functional impairment.
METHODS: This study was a retrospective cohort study. A total of 115 patients diagnosed with urolithiasis and treated at our hospital were enrolled. According to the surgical procedure used, patients were assigned to a control group [n = 57, received extracorporeal shock wave lithotripsy (ESWL)], and a study group (n = 58, underwent holmium laser lithotripsy]. Baseline characteristics were compared. Postoperative complication rates, treatment efficacy, operative indicators (operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and hospital stay), and levels of inflammatory markers (C-reactive protein [CRP], procalcitonin [PCT]), and renal function indicators (serum creatinine [Scr]) were measured before surgery and one day postoperatively.
RESULTS: No significant differences were noted in baseline characteristics between the two groups (P > 0.05). The study group demonstrated a lower incidence of postoperative complications, a higher overall effective treatment rate, as well as lower operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and length of hospital stay (P < 0.05) relative to the control group. One day post-surgery, CRP, PCT, and Scr levels increased in both groups relative to preoperative values (P < 0.05), but the elevations were significantly lower in the study group (P < 0.05).
CONCLUSION: Holmium laser lithotripsy effectively decreases the incidence of postoperative complications in patients with urolithiasis, improves therapeutic outcomes, reduces surgical trauma, alleviates postoperative inflammatory responses, and mitigates renal functional impairment.